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David Perlmutter, MD, FACN, ABIHM
Glutamine also affects ROS homeostasis through production of NADPH via GLUD 114 , and at least two other related mechanisms 31, 34 where TCA cycle-derived aspartate or malate is exported to the cytoplasm and then converted to pyruvate to produce NADPH through the malic enzymes, provide reducing equivalents for glutathione
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