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The ligand’s 2D structure was converted to an optimized 3D conformation using Chem3D (ChemOffice 19.0) and saved in mol2 format
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Published in vivo studies have indicated that elevated Ggt1 activity along with cellular glutathione depletion are associated with the increased oxidative stress induced by estrogen deficiency under ovariectomy or menopause conditions (Wei et al., 2014
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